Nature Protocols

Setting the Benchmark: a comprehensive database of peer-reviewed, step-by-step protocols from leading laboratories

Nature Protocols is an online journal of laboratory protocols for bench researchers. Protocols are presented in a ‘recipe’ style providing step-by-step descriptions of procedures, which users can take to the lab and immediately apply in their own research. Protocols on the site are fully searchable and organized into logical categories to be easily accessible to researchers.

Nature Protocols appeals to a broad audience from researchers and technical staff to postdoctoral fellows and faculty interested in biomedicine, biological sciences and chemistry at academic, commercial and governmental organizations and research institutions. 

Nature Protocols is complimented by the sister journal, Nature Methods, which predominantly publishes primary research articles focused on novel methods and improvements to tried-and-tested techniques.


Nature protocols (1)
Nature protocols (1)
(PDF, 698.52 KB)
Nature methods (1)
Nature methods (1)
(PDF, 484.11 KB)

Benefits of access

  • A comprehensive database of thousands of peer-reviewed, step-by-step protocols from leading laboratories
  • A resource that covers the breadth of the biological and biomedical sciences fields, including some chemistry/physics techniques with biological applications
  • A single resource that publishes a mix of well-established, widely-used lab protocols and more cutting-edge procedures.
  • By covering both established and relatively novel techniques, we provide a valuable resource for users at all stages of research (whether setting up a lab, optimizing their existing protocols, using/adapting new techniques, branching out into new areas of research, etc.)
  • Each protocol is written in an easy-to-follow format and contains a materials list, troubleshooting tips, critical steps, safety precautions and instructional videos that describe the advantages, limitations and potential applications of the technique
  • Ability to download the fully formatted PDF to take directly to the bench
  • Mobile optimized content – Nature Protocols offers fully mobile-optimized articles, enabling users to access site license content from their personal devices

Subject areas

  • Biochemistry
  • Cell biology
  • Cell culture
  • Chemical modification
  • Computational biology
  • Developmental biology
  • Epigenomics
  • Genetic analysis
  • Genetic modification
  • Genomics
  • Imaging
  • Immunology
  • Isolation, Purification and Separation
  • Lipidomics
  • Metabolomics
  • Microbiology
  • Model organisms
  • Nanotechnology
  • Neuroscience
  • Nucleic acid based molecular biology
  • Pharmacology
  • Plant biology
  • Protein analysis
  • Proteomics
  • Spectroscopy
  • Structural biology
  • Synthetic chemistry
  • Tissue culture

Additional information


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