This paper focuses on the regulation of higher-order chromatin as an essential element for tissue-specific patterns of gene expression.
Creating genetically engineered non-transgenic plants.
Journal of Biological Research - Thessaloniki
In this review article, summary statistics and software tools are presented and classified according to (1) the selective sweep signature they detect and (2) their capacity to analyze whole genomes or subgenomic regions. As such, it’s a must-read for bioinformaticians and evolutionary scientists alike.
Nature Reviews Molecular Cell Biology
A update on the progress in making blood stem cells in vitro, which has broad applications in basic research and clinical medicine, e.g. for therapies involving the transplantation and transfusion of blood cells.
Puts forward a unique concept on how our mouths evolved.
Interdisciplinary Sciences: Computational Life Sciences
An algorithm solving the non-classical case of SBH, where the chip probes consist in a set of oligonucleotides described by some specific pattern.
Applied research confirms that arbuscular mycorrhizal fungi can be used to reduce inorganic fertilizer use and improve yield in commercial field production.
Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology)
A significant new technology for olefin polymerization fluidized bed reactors based on acoustic emissions has demonstrated impressive reliability for stable operation.
Clinical Autonomic Research
A key paper to understanding temperature and autonomic changes in women depending on their hormonal status.
This article provides key science-based management and conservation measures to ensure the viability and endurance of sustainable ungulate populations in Europe.
Molecular Imaging and Biology
Imaging modality is non-invasive and not dependent on radiation. As such, the methodology should be much more broadly applied.
This paper deals with a very hot topic: how DNA and the genome are structured and expressed.
Acta Pharmacologica Sinica
Conjugated polymer nanomaterials hold great promise for biomedical imaging, noninvasive therapy, and drug delivery applications.
Indian Journal of Microbiology
Puts forward an eco-friendly process for managing waste to reduce greenhouse gases and pathogens - two of the greatest concerns for Environmental and Health Departments.
The authors demonstrate that the isotopic ratio of 13C to 12C stored in wood offers a reliable indicator of drought across a wide range of tree species and environmental conditions. Understanding how trees respond to drought is critical to forecasting both the short-term and long-term impacts of climate change on forests.
Journal of Cardiovascular Translational Rsearch
This outstanding article describes a new method for identifying the mutations that lead to inherited cardiac diseases.
The ISME Journal
The work reported by Neave et al. yields valuable new insights into how prokaryotic endosymbionts are shaped in corals and how they contribute to host functions.
Behavioral Eology and Sociobiology
The experimental finding that women with higher scores on the domestic violence factor preferred significantly less masculine Colombian male faces is highly relevant and significant in the current #MeToo public debate.
A must-read article that describes the new concept of dosage compensation in the context of regulating the sexual dimorphism and evolution of sex chromosomes.
Plant Cell Tissue and Organ Culture: Journal of Plant Biotechnology
CRISPR/Cas9 excised a 1.6 kb transgene fragment from the rice chromosome, developing mono-allelic and bi-allelic excisions and yielding marker-free plants.
Nature Reviews Immunology
Environmental experiences during childhood can result in the development of allergies that persist into adulthood. Knowledge of these early-life exposures may help to inform the treatment and prevention of allergies.
Journal of Natural Medicines
Provides must-read advice for researchers on pharmacological studies of Kampo medicines containing Ephedra herba.
The Journal of Molecular Evolution
Can we resurrect ancient genes? Here, Kacar et al. show that, with the aid of directed evolution, we can make hybrid proteins that both inform evolutionary history and the creation of novel activities.
Plant and Soil
Biofortification of plants with micronutrients holds tremendous potential to improve the quality of food for humans, and of feed for farm animals.
Nature Cell Biology
An analysis of human hematopoiesis at single-cell resolution shows that hematopoietic stem cell lineage commitment is a continuous process, unlike the traditionally accepted model of stepwise progression through distinct stem and progenitor states.
How long can a human life be? Is it finite or potentially infinite? The authors provide statistical evidence for a potentially unlimited lifespan.
On-and-off fasting can help combat obesity and metabolic diseases.
Biological Trace Element Research
A must-read paper for cancer researchers, which shows the difference between carcinogenic trace elements interacting with DNA and with its environment.
This research holds great potential for the early identification of breast cancer and may lead to earlier diagnosis and treatment.
This article addresses the importance of microbes in health, and in serious conditions such as autisms.
Insects are fascinating life forms that are all around us and play crucial roles in our ecosystems - this new technique could considerably expand our understanding of insects.
Cancer Immunology Immunotherapy
Overcoming dysfunction of a novel and rarely studied immune cell type may be important for controlling metastatic cancer.
Cell Biology and Toxicology
An innovative approach to cell biology and toxicology, which could challenge our assumptions and open a new world of drug discovery and development.
Nature Reviews Microbiology
Offers a proactive guide to identifying and mitigating the global threat posed by antibiotic resistance.
Signal Transduction and Targeted Therapy
Demonstrates that white blood cells produce pro-regenerative factors that can help the liver recover from injury.
Journal of Assisted Reproduction and Genetics
After a year of gene editing in human embryos this paper reveals that a common feature of human embryos is correctable after transfer of one patient’s polar body (genome) into the cytoplasm of a donor oocyte. This finding opens a whole new avenue of potential therapeutic interventions.
Increasing a transcriptional coactivator can successfully reduce neuronal death caused by amyloid beta in the context of Alzheimer’s disease.
Australasian Physical & Engineering Sciences in Medicine
Introduces a novel method for detecting atrial fibrillation using the ECG signal.
The authors highlight ethically problematic trends in scientific analyses of food security, and show how easily the message can become biased.
Proposes a promising new treatment for congestive heart failure.
npj Regenerative Medicine
These findings suggest that drugs used to treat neurological and psychiatric diseases could be repurposed to augment the innervation, integration, and function of organs transplanted in regenerative therapies.
This review introduces readers to the roles of Notch and ASCL1 in the biology of small cell lung cancer, providing potential therapeutic targets for this recalcitrant cancer.
Discusses the production of a new type of biologically active compounds in a group of microorganisms that have traditionally been overlooked.
Sound is an essential component of the environment, and provides the conditions and information needed to preserve many animals’ and ecosystems’ health.
Femtosecond laser fabrication: realizing dynamic control of electrons.
Cellular & Molecular Immunology
Investigates the mechanism of UC MSCs in the regulation of peripheral regulatory T (Treg) cells and T helper 17 (Th17) cells in patients with systemic lupus erythematosus.
Cell Stress & Chaperones
This paper discusses the role of a key protein’s functional plasticity in preventing diseases associated with aging.
This article presents two major aspects leading to human cooperation: cooperative breeding, which produces ontogenetic preadaptations for collaboration during infancy that later prove useful for older children and adults; and interdependent collaboration during adulthood, which puts pressure on ever-younger children to begin acquiring and practicing their collaborative skills. For the full story, we need both the phylogeny and ontogeny, and how they relate.
Journal of Plant Diseases and Protection
This paper discusses the risks posed by the introduction of biological control agents and strongly suggests including secondary metabolite gene cluster expression data in the list of information required for approving plant protection agents and releasing them to the field.
Infectious diseases are the world’s biggest killer of children and young adults. There is a substantial demand for models that mimic the structure-function and multicellular complexity of endogenous tissues . Advanced 3-D intestinal co-culture models containing multiple epithelial cell types and inflammatory immune cells were engineered under physiological fluid flow conditions, validated, and applied to study infection by Salmonella pathovars with different host adaptations, disease phenotypes, and antibiotic resistance.
Introducing a new way to treat organophosphate-induced nerve damage.
European Journal of Clinical Microbiology & Infectious Diseases
Real-time PCR analysis of oropharyngeal samples is compared to conventional testing for the diagnosis of bacterial pneumonia caused by S. pneumoniae or H. influenzae.
Food Security: the science, sociology and economics of food production and access to food
With nearly 3 billion people suffering from hunger or hidden hunger, and with current food production methods being non-sustainable, Peter Horton shows what steps need to be taken.
A must-read paper for those who concern feeding the ever increasing world population under the growing water scarcity situation.