3D genomes

Browse key articles nominated by our Editors

3D clustering of co-regulated genes and its effect on gene expression 

from Current Genetics
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3D genome of multiple myeloma reveals spatial genome disorganization associated with copy number variations

from Nature Communications

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3D genomics imposes evolution of the domain model of eukaryotic genome organization

from Chromosoma

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A transient pool of nuclear F-actin at mitotic exit controls chromatin organization

from Nature Cell Biology

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Condensin-mediated remodeling of the mitotic chromatin landscape in fission yeast

from Nature Genetics

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Evolutionary dynamics of 3D genome architecture following polyploidization in cotton

from Nature Plants

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Genome-wide mapping and analysis of chromosome architecture

from Nature Reviews Molecular Cell Biology

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Hi-C-constrained physical models of human chromosomes recover functionally-related properties of genome organization

from Scientific Reports

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Histone H3 lysine 4 monomethylation modulates long-range chromatin interactions at enhancers

from Cell Research

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Large scale genomic reorganization of topological domains at the HoxD locus

from Genome Biology

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Long non-coding RNAs: spatial amplifiers that control nuclear structure and gene expression

from Nature Reviews Molecular Cell Biology

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Mixing genomes alters nuclear architecture

from Nature Plants

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Molecular mechanism of directional CTCF recognition of a diverse range of genomic sites

from Cell Research

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Not just gene expression: 3D implications of chromatin modifications during sexual plant reproduction

from Plant Cell Reports

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Organization and function of the 3D genome

from Nature Reviews Genetics

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Polymer physics of chromosome large-scale 3D organisation

from Scientific Reports

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Potential energy landscapes identify the information-theoretic nature of the epigenome

from Nature Genetics

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Regulation of genome organization and gene expression by nuclear mechanotransduction

from Nature Reviews Molecular Cell Biology

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Single-molecule sequencing and Hi-C-based proximity-guided assembly of amaranth (Amaranthus hypochondriacus) chromosomes provide insights into genome evolution

from BMC Biology

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SMC complexes orchestrate the mitotic chromatin interaction landscape

from Current Genetics

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The X chromosome in space

from Nature Reviews Genetics

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Tissue-specific CTCF–cohesin-mediated chromatin architecture delimits enhancer interactions and function in vivo

from Nature Cell Biology

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Topological organization and dynamic regulation of human tRNA genes during macrophage differentiation

from Genome Biology

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Topologically associating domains are ancient features that coincide with Metazoan clusters of extreme noncoding conservation

from Nature Communications

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Also see the 3D Genome Collection

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