DNA methylation/epigenetics

Browse key articles nominated by our Editors

A streamlined method for analysing genome-wide DNA methylation patterns from low amounts of FFPE DNA

from BMC Medical Genomics

L_brandstrip_bmc​​​​​​​

A user's guide to the ambiguous word 'epigenetics'

from Nature Reviews Molecular Cell Biology

L_natureresearch_mini_logo

Aberrant DNA Methylation in Chronic Myeloid Leukemia: Cell Fate Control, Prognosis, and Therapeutic Response

from Biochemical Genetics

L_springer_mini_logo

 

Ageing-associated DNA methylation dynamics are a molecular readout of lifespan variation among mammalian species

from Genome Biology

L_brandstrip_bmc

 

Altered DNA methylation in liver and adipose tissues derived from individuals with obesity and type 2 diabetes

from BMC Medical Genetics

L_brandstrip_bmc

 

An epigenome-wide methylation study of healthy individuals with or without depressive symptoms

from Journal of Human Genetics

An interplay between plasticity and parental phenotype determines impacts of ocean acidification on a reef fish

from Nature Ecology & Evolution

L_natureresearch_mini_logo

Apigenin Reactivates Nrf2 Anti-oxidative Stress Signaling in Mouse Skin Epidermal JB6 P + Cells Through Epigenetics Modifications

from The AAPS Journal

L_springer_mini_logo

Baf60b-mediated ATM-p53 activation blocks cell identity conversion by sensing chromatin opening

from Cell Research

Braf, Kras and Helicobacter pylori epigenetic changes-associated chronic gastritis in Egyptian patients with and without gastric cancer

from World Journal of Microbiology and Biotechnology

L_springer_mini_logo

C. elegans SUP-46, an HNRNPM family RNA-binding protein that prevents paternally-mediated epigenetic sterility

from BMC Biology

L_brandstrip_bmc

Chromatin marks shape mutation landscape at early stage of cancer progression

from npj Genomic Medicine

L_natureresearch_mini_logo

Conserved noncoding sequences conserve biological networks and influence genome evolution

from Heredity

CpG methylation patterns of human mitochondrial DNA

from Scientific Reports

L_natureresearch_mini_logo

Critical genomic regulation mediated by Enhancer of Polycomb

from Current Genetics

L_springer_mini_logo

Cross-tissue integration of genetic and epigenetic data offers insight into autism spectrum disorder

from Nature Communications

L_natureresearch_mini_logo

De novo DNA methylation drives 5hmC accumulation in mouse zygotes

from Nature Cell Biology

L_natureresearch_mini_logo

Defense against territorial intrusion is associated with DNA methylation changes in the honey bee brain

from BMC Genomics

L_brandstrip_bmc​​​​​​​

Detecting TF-miRNA-gene network based modules for 5hmC and 5mC brain samples: a intra- and inter-species case-study between human and rhesus

from BMC Genetics

L_brandstrip_bmc

DNA methylation and chromatin accessibility profiling of mouse and human fetal germ cells

from Cell Research

DNA methylation in blood from neonatal screening cards and the association with BMI and insulin sensitivity in early childhood

from International Journal of Obesity

DNA methylation in schizophrenia in different patient-derived cell types

from npj Schizophrenia

L_natureresearch_mini_logo

DNA methylation is dispensable for changes in global chromatin architecture but required for chromocentre formation in early stem cell differentiation

from Chromosoma

L_springer_mini_logo

DNA methylation profile is associated with the osteogenic potential of three distinct human odontogenic stem cells

from Signal Transduction and Targeted Therapy

DNA Methylation Profiles of Organic Anion Transporting Polypeptide 1B3 in Cancer Cell Lines

from Pharmaceutical Research

L_springer_mini_logo

DNMT and HDAC inhibitors induce cryptic transcription start sites encoded in long terminal repeats

from Nature Genetics

L_natureresearch_mini_logo

Dust mite allergen-specific immunotherapy increases IL4 DNA methylation and induces Der p-specific T cell tolerance in children with allergic asthma

from Cellular and Molecular Immunology

Elevated polygenic burden for autism is associated with differential DNA methylation at birth

from Genome Medicine

L_brandstrip_bmc

Empirical comparison of reduced representation bisulfite sequencing and Infinium BeadChip reproducibility and coverage of DNA methylation in humans

from npj Genomic Medicine

L_natureresearch_mini_logo

Epigenetic differences between naïve and primed pluripotent stem cells

from Cellular and Molecular Life Sciences

L_springer_mini_logo

Epigenetic Regulation of Organic Anion Transporting Polypeptide 1B3 in Cancer Cell Lines

from Pharmaceutical Research

L_springer_mini_logo​​​​​​​

Epigenetic supersimilarity of monozygotic twin pairs

from Genome Biology

L_brandstrip_bmc

Epigenetic transcriptional memory

from Current Genetics

L_springer_mini_logo

Genome-wide DNA methylation is predictive of outcome in juvenile myelomonocytic leukemia

from Nature Communications

L_natureresearch_mini_logo

Histone deacetylase inhibitors VPA and TSA induce apoptosis and autophagy in pancreatic cancer cells

from Cellular Oncology

L_springer_mini_logo

Hypomethylation of interleukin-6 (IL-6) gene increases the risk of essential hypertension: a matched case–control study

from Journal of Human Hypertension

Inhibition of histone deacetylases sensitizes glioblastoma cells to lomustine

from Cellular Oncology

L_springer_mini_logo

Integrated analysis of DNA-methylation and gene expression using high-dimensional penalized regression: a cohort study on bone mineral density in postmenopausal women

from BMC Medical Genomics

L_brandstrip_bmc

Intratumoral heterogeneity identified at the epigenetic, genetic and transcriptional level in glioblastoma

from Scientific Reports

L_natureresearch_mini_logo

Kagami–Ogata syndrome: a clinically recognizable upd(14)pat and related disorder affecting the chromosome 14q32.2 imprinted region

from Journal of Human Genetics

​​​​​​​

Metabolic control of T-cell immunity via epigenetic mechanisms

from Cellular and Molecular Immunology

Metabolic regulation of gene expression through histone acylations

from Nature Reviews Molecular Cell Biology

L_natureresearch_mini_logo

MethCNA: a database for integrating genomic and epigenomic data in human cancer

from BMC Genomics

L_brandstrip_bmc

Phytochemicals from Cruciferous Vegetables, Epigenetics, and Prostate Cancer Prevention

from The AAPS Journa

L_springer_mini_logo

Phytopathogen-induced changes to plant methylomes

from Plant Cell Reports

L_springer_mini_logo

Precision cancer therapy is impacted by oncogene-dependent epigenome remodeling

from npj Precision Oncology

L_natureresearch_mini_logo

RNA-directed DNA methylation involves co-transcriptional small-RNA-guided slicing of polymerase V transcripts in Arabidopsis

from Nature Plants

L_natureresearch_mini_logo

rs9939609 FTO genotype associations with FTO methylation level influences body mass and telomere length in an Australian rural population

from International Journal of Obesity

Starting embryonic transcription for the first time

from Nature Genetics

L_natureresearch_mini_logo​​​​​​​

Statistical and integrative system-level analysis of DNA methylation data

from Nature Reviews Genetics

L_natureresearch_mini_logo

Synergistic anti-cancer effects of epigenetic drugs on medulloblastoma cells

from Cellular Oncology

L_springer_mini_logo

The DNA methyltransferase family: a versatile toolkit for epigenetic regulation

from Nature Reviews Genetics

L_natureresearch_mini_logo

The epigenetic memory of temperature during embryogenesis modifies the expression of bud burst-related genes in Norway spruce epitypes

from Planta

L_springer_mini_logo

The gymnastics of epigenomics in rice

from Plant Cell Reports

L_springer_mini_logo

The impact of cellular metabolism on chromatin dynamics and epigenetics

from Nature Cell Biology

L_natureresearch_mini_logo

The molecular basis of the organization of repetitive DNA-containing constitutive heterochromatin in mammals

from Chromosome Research

L_springer_mini_logo

The TET enzymes

from Cellular and Molecular Life Sciences

L_springer_mini_logo

Unique cell-type-specific patterns of DNA methylation in the root meristem

from Nature Plants

L_natureresearch_mini_logo

Widespread adenine N6-methylation of active genes in fungi

from Nature Genetics

L_natureresearch_mini_logo

Worldwide patterns of human epigenetic variation

from Nature Ecology & Evolution

L_natureresearch_mini_logo