DNA structure & function

Browse key articles nominated by our Editors

A DNA aptamer recognising a malaria protein biomarker can function as part of a DNA origami assembly

from Scientific Reports

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A proof of the DBRF-MEGN method, an algorithm for deducing minimum equivalent gene networks

from Source Code for Biology and Medicine

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Amphioxus SYCP1: a case of retrogene replacement and co-option of regulatory elements adjacent to the ParaHox cluster

from Development Genes and Evolution

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Arabidopsis ATAF1 enhances the tolerance to salt stress and ABA in transgenic rice

from Journal of Plant Research

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ATM and CDK2 control chromatin remodeler CSB to inhibit RIF1 in DSB repair pathway choice

from Nature Communications

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Bioinformatics analyses of Shigella CRISPR structure and spacer classification

from World Journal of Microbiology and Biotechnology

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Biological function in the twilight zone of sequence conservation

from BMC Biology

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Characterization of DNA degradation using direct current conductivity and dynamic dielectric relaxation techniques

from AAPS PharmSciTech

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Chromosome conformation capture technologies and their impact in understanding genome function

from Chromosoma

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Cryo-EM structure of human DNA-PK holoenzyme

from Cell Research

De novo transcriptome assembly and characterization of nine tissues of Lonicera japonica to identify potential candidate genes involved in chlorogenic acid, luteolosides, and secoiridoid biosynthesis pathways

from Journal of Natural Medicines

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Dendritic Cells Targeting and pH-Responsive Multi-layered Nanocomplexes for Smart Delivery of DNA Vaccines

from AAPS PharmSciTech

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Detecting copy-number variations in whole-exome sequencing data using the eXome Hidden Markov Model: an ‘exome-first’ approach

from Journal of Human Genetics

DNA-based therapeutics and DNA delivery systems: A comprehensive review

from The AAPS Journal

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Dynamic basis for dG•dT misincorporation via tautomerization and ionization

from Nature

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Extracellular DNA and autoimmune diseases

from Cellular and Molecular Immunology

Genome analysis reveals insights of the endophytic Bacillus toyonensis BAC3151 as a potentially novel agent for biocontrol of plant pathogens

from World Journal of Microbiology and Biotechnology

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Genome-wide characterization of mammalian promoters with distal enhancer functions

from Nature Genetics

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High-fat diet modifies expression of hepatic cellular senescence gene p16(INK4a) through chromatin modifications in adult male rats

from Genes & Nutrition

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Hypoxia-driven splicing into noncoding isoforms regulates the DNA damage response

from npj Genomic Medicine

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In Vitro Functional Characterisation of Cytochrome P450 (CYP) 2C19 Allelic Variants CYP2C19*23 and CYP2C19*24

from Biochemical Genetics

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Inferring the physical properties of yeast chromatin through Bayesian analysis of whole nucleus simulations

from Genome Biology

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Interplay of space radiation and microgravity in DNA damage and DNA damage response

from npj Microgravity

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Intracellular Gene Transfer in Rats by Tail Vein Injection of Plasmid DNA

from The AAPS Journal

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Invisible cities: segregated domains in the yeast genome with distinct structural and functional attributes

from Current Genetics

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Isolation and characterisation of the epothilone gene cluster with flanks from high alkalotolerant strain Sorangium cellulosum (So0157-2)

from World Journal of Microbiology and Biotechnology

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Lanthanum induced B-to-Z transition in self-assembled Y-shaped branched DNA structure

from Scientific Reports

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Maintenance of genome stability: the unifying role of interconnections between the DNA damage response and RNA-processing pathways

from Current Genetics

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Mouse embryonic stem cells have increased capacity for replication fork restart driven by the specific Filia-Floped protein complex

from Cell Research

Nephele: genotyping via complete composition vectors and MapReduce

from Source Code for Biology and Medicine

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Nuclear morphologies: their diversity and functional relevance

from Chromosoma

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On causal roles and selected effects: our genome is mostly junk

from BMC Biology

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Predicting chromatin architecture from models of polymer physics

from Chromosome Research

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Primordial origin and diversification of plasmids in Lyme disease agent bacteria

from BMC Genomics

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Segregation of mitochondrial DNA heteroplasmy through a developmental genetic bottleneck in human embryos

from Nature Cell Biology

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Selective Y centromere inactivation triggers chromosome shattering in micronuclei and repair by non-homologous end joining

from Nature Cell Biology

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Single-cell replication profiling to measure stochastic variation in mammalian replication timing

from Nature Communications

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Sparse conserved under-methylated CpGs are associated with high-order chromatin structure

from Genome Biology

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Sperm DNA damage—the effect of stress and everyday life factors

from International Journal of Impotence Research

The effects of miRNA-145 on the phenotypic modulation of rat corpus cavernosum smooth muscle cells

from International Journal of Impotence Research

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The human noncoding genome defined by genetic diversity

from Nature Genetics

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The multifaceted roles of PARP1 in DNA repair and chromatin remodelling

from Nature Reviews Molecular Cell Biology

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The Y chromosome: a blueprint for men’s health?

from European Journal of Human Genetics

Transcription–replication conflicts: how they occur and how they are resolved

from Nature Reviews Molecular Cell Biology

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Variation of rDNA Internal Transcribed Spacer Sequences in Rhizoctonia cerealis

from Current Microbiology

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Viral evasion of DNA-stimulated innate immune responses

from Cellular & Molecular Immunology