Spotlight on: Precision Medicine

Read key articles from our Academic Journals

Our Editors are proud to highlight over 50 articles across a range of specialties which are advancing research in this area. 

Read over

  • 50

    outstanding articles

The general notion of Precision Medicine has long been of interest to both researchers and clinicians. After all, it has always been the goal of clinicians to tailor treatments to the unique context of their patients.  However, we are now seeing enhanced potential for tailored approaches to the care of individuals due, in part, to an unprecedented ability to define the genomic characteristics of patients. Technologies such as chromosomal microarray analysis, broad genotyping and genome scale sequencing can now define susceptibilities, risks and diagnoses more accurately than ever before.

James P. Evans, Editor-in-Chief, Genetics in Medicine

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All articles not published open access are free to read until November 15, 2017.

APS Journal

Therapeutic gene editing: delivery and regulatory perspectives

Genome-wide analysis of microRNA and mRNA expression signatures in cancer

AJG Journal

An Evaluation of Factors Associated With Pathogenic PRSS1, SPINK1, CTFR, and/or CTRC Genetic Variants in Patients With Idiopathic Pancreatitis

A Serological Biopsy Using Five Stomach-Specific Circulating Biomarkers for Gastric Cancer Risk Assessment: A Multi-Phase Study

BJC Journal

Clinical study of genomic drivers in pancreatic ductal adenocarcinoma

Development of a gene panel for next-generation sequencing of clinically relevant mutations in cell-free DNA from cancer patients

CGT Journal

New methods in the diagnosis of cancer and gene therapy of cancer based on nanoparticles

An AAVP-based solid-phase transducing matrix for transgene delivery: potential for translational applications

CDD Journal

Culling of APCs by inflammatory cell death pathways restricts TIM3 and PD-1 expression and promotes the survival of primed CD8 T cells

Ageing and hypoxia cause protein aggregation in mitochondria

CDDIS Journal

Precision medicine for hepatocelluar carcinoma using molecular pattern diagnostics: results from a preclinical pilot study

Enhanced neuroprotective efficacy of bone marrow mesenchymal stem cells co-overexpressing BDNF and VEGF in a rat model of cardiac arrest-induced global cerebral ischemia


CR Journal

Blocking the recruitment of naive CD4+ T cells reverses immunosuppression in breast cancer

Improved survival of porcine acute liver failure by a bioartificial liver device implanted with induced human functional hepatocytes


CMI Journal

Loss of T-cell protein tyrosine phosphatase in the intestinal epithelium promotes local inflammation by increasing colonic stem cell proliferation

Proteasome inhibition suppresses Th17 cell generation and ameliorates autoimmune development in experimental Sjögren’s syndrome


EJCN Journal

Novel approaches for the promotion of physical activity and exercise for prevention and management of type 2 diabetes

GT Journal

How the discovery of ISS-N1 led to the first medical therapy for spinal muscular atrophy

The clinical landscape for SMA in a new therapeutic era

GIM Journal

Genomic diagnostics within a medically underserved population: efficacy and implications

Making genomic medicine evidence-based and patient-centered: a structured review and landscape analysis of comparative effectiveness research

HR Journal

Relationships between retinal arteriole anatomy and aortic geometry and function and peripheral resistance in hypertensives

IJO Journal

Increased risk of influenza among vaccinated adults who are obese

The development of scientific evidence for health policies for obesity: why and how?

JES Journal

Preparation and performance features of wristband samplers and considerations for chemical exposure assessment

Associations among personal care product use patterns and exogenous hormone use in the NIEHS Sister Study

JHG Journal

Human genetic variation database, a reference database of genetic variations in the Japanese population

The genomic dynamics during progression of lung adenocarcinomas


JHH Journal

Are genetic polymorphisms in the renin-angiotensin-aldosterone system associated with essential hypertension?


JP Journal

Generation and validation of a universal perinatal database and biospecimen repository: PeriBank

Effect of genetic variants of bilirubin metabolism on the degree of hyperbilirubinemia in African-American newborns


Leukemia Journal

BET protein bromodomain inhibitor-based combinations are highly active against post-myeloproliferative neoplasm secondary AML cells

PR1 peptide vaccine induces specific immunity with clinical responses in myeloid malignancies


Modern Pathology Journal

Diagnostic and predictive biomarkers for lymphoma diagnosis and treatment in the era of precision medicine


MP Journal

An update on stem cell biology and engineering for brain development


MI Journal

Genetics of eosinophilic esophagitis

Genetic control of autophagy underlies pathogenesis of inflammatory bowel disease

NPP Journal

Opioid-Sparing Effect of Cannabinoids: A Systematic Review and Meta-Analysis

Harnessing Smartphone-Based Digital Phenotyping to Enhance Behavioral and Mental Health

Oncogene Journal

Effective personalized therapy for breast cancer based on predictions of cell signaling pathway activation from gene expression analysis

Nucleic acid targeting: towards personalized therapy for head and neck cancer

PR Journal

Renal injury in neonates: use of “omics” for developing precision medicine in neonatology

Urotensin 2 in Kawasaki disease pathogenesis

Prostate Cancer Journal

Utilization of biopsy-based genomic classifier to predict distant metastasis after definitive radiation and short-course ADT for intermediate and high-risk prostate cancer

Decipher correlation patterns post prostatectomy: initial experience from 2342 prospective patients

TPJ Journal

Cytochrome P450 interactions are common and consequential in Massachusetts hospital discharges

The influence of FCGR2A and FCGR3A polymorphisms on the survival of patients with recurrent or metastatic squamous cell head and neck cancer treated with cetuximab

Springer Pharmaceutical Research Journal

Also look at Pharmaceutical Research from our sister company, Springer

Personalized Therapeutics and Pharmacogenomics: Integral to Personalized Health Care