Preventing Disease in the 21st Century

Editor picks from our academic journals on nature.com

Our esteemed editors have picked out the best recently published research to help prevent disease in the 21st century.  Journal titles featured include Pediatric Research, Oncogene and Genes & Immunity. 

Presenting

  • 30+

    outstanding pieces of research

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Cynthia F. Bearer, MD, PhD - Editor-in-Chief, Pediatric Research

"Preventing Disease in the 21st Century is a pathway to improve health and reduce cost, two imperative issues for the next century. The exciting new strategies are as broad as genetic and epigenetic therapy to reducing global pollution and involve techniques from vaccine development to reducing technoference.  With such a broad reach, topics of interest are diverse and interdisciplinary, and will reach far beyond the classic field of medicine."

Start reading... all non open-access content is free to view until May 15th

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An educational intervention for NICU staff decreased maternal postpartum depression


Stoss therapy using fortified biscuit for vitamin D-deficient children: a novel treatment

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Challenges in managing graft-versus-host disease in developing countries: a perspective

Post-remission strategies for the prevention of relapse following allogeneic hematopoietic cell transplantation for high-risk acute myeloid leukemia


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Anlotinib as a third-line therapy in patients with refractory advanced non-small-cell lung cancer

Inhibition of SIRT1 deacetylase and p53 activation uncouples the anti-inflammatory and chemopreventive actions of NSAIDs


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Clinical impact and cost-effectiveness of a 176-condition expanded carrier screen

Estimating the burden and economic impact of pediatric genetic disease



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Azacitidine is effective for targeting leukemia-initiating cells in juvenile myelomonocytic leukemia

The prognostic potential of monitoring disease dynamics in NPM1-positive acute myeloid leukemia



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A diet enriched with curcumin promotes resilience to chronic social defeat stress


Digital devices and continuous telemetry: opportunities for aligning psychiatry and neuroscience

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Connexins in cancer: bridging the gap to the clinic

Targeting SYK signaling in myeloid cells protects against liver fibrosis and hepatocarcinogenesis

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Interventions and public health nutrition effectiveness of interventions aimed at improving dietary behaviours among people at higher risk of or with chronic non-communicable diseases

Prevention of type 2 diabetes—success story that is waiting for next steps

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An innovative visual acuity chart for urgent and primary care settings

Diagnostic algorithm utilising multimodal imaging including optical coherence tomography angiography for the detection of myopic choroidal neovascularisation

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Effects of bariatric surgery on retinal microvascular architecture in obese patients

Working toward precision medicine approaches to treat severe obesity in adolescents


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Activation of mTORC1 in subchondral bone preosteoblasts promotes osteoarthritis by stimulating bone sclerosis and secretion of CXCL12

Efficacy of an orally active small-molecule inhibitor of RANKL in bone metastasis

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A framework for estimating the US mortality burden of fine particulate matter exposure attributable to indoor and outdoor microenvironments

Flame retardant exposure assessment: findings from a behavioral intervention study

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An important step on the long path to clinical application of in utero gene therapy

scFv6.C4 DNA vaccine with fragment C of Tetanus toxin increases protective immunity against CEA-expressing tumor


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Maintenance use of aspirin or other non-steroidal anti-inflammatory drugs (NSAIDs) and prostate cancer risk

Serum cholesterol and risk of high-grade prostate cancer: results from the REDUCE study

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Gut microbiota in adolescents and the association with fatty liver: the EPOCH study

The association of ambient PM2.5 with school absence and symptoms in schoolchildren: a panel study

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Primary immunodeficiency diseases in a tuberculosis endemic region: challenges and opportunities

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Sex-associated preventive effects of low-dose aspirin on obesity and non-alcoholic fatty liver disease in mouse offspring with over-nutrition in utero

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Integrative approach to sporadic Alzheimer’s disease

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Pharmacogenomics in epithelial ovarian cancer first-line treatment outcome

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Prevalence and correlates of erectile dysfunction in type 2 diabetic men

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