HILIC, SFC and other polar separation techniques

Contents Polar Chromatography

• Apparatus setup of HPLC and SFC
• Basic terms in IC, HILIC and SFC
• Basic concepts in further polar chromatography techniques

Content HILIC(-MS)

• Separation and detection of very polar molecules with HILIC-MS
• Stationary HILIC phases (for MS coupling)
• Mobile HILIC phases (for MS coupling)
• Other necessary conditions for MS coupling

Contents SFC(-MS)

• Separation and detection of very polar molecules with SFC-MS
• Stationary SFC phases (for MS coupling)
• Mobile SFC phases (for MS coupling)
• Other necessary conditions for MS coupling
• Content Application of polar chromatography
• Examples from the fields of bioanalysis, environmental analysis and food analysis
• Screening approaches for polar molecules
• Examples of course participants (if known in advance)

Contents Chromatographic couplings

• LC-LC-MS systems for the simultaneous detection of molecules of different polarity
• RPLC-HILIC-MS: structure and application
• 2D- LC-MS: structure and application

Your top speaker: PD Dr. habil. Thomas Letzel

PD Dr. Thomas Letzel was trained as a chemical laboratory technician, has studied chemistry in Munich and worked on his Ph.D. thesis in the field of environmental analysis at the Technical University of Munich. After a post-doctoral stay in pharmaceutical analysis at the VU Amsterdam, he was head of the analytical and biochemical research group (AFG) at the Technical University of Munich (TUM) from 2003 to 2018 and held a teaching professorship in pharmaceutical analysis at the Ludwig-Maximilians University in Munich from 2014 to 2017.
Since 2018 he is also one of the executive directors at the start-up company ‘Analytisches Forschungsinstitut fuer Non-Target Screening’ (AFIN-TS GmbH). In AFIN-TS he continues basic and advanced research in analytical chemistry and simultaneously consults, supports and teaches common instrumental analysis, such as LC-MS, GC-MS, etc., as well as HILIC, RPLC-HILIC, SFC, and non-target screening solutions (also for commercial partners).
In the past 30 years, he has devoted himself to teaching and imparting knowledge about chromatographic and mass spectrometric analysis, as well as applications in various research areas, such as environmental and food analysis, as well as pharmaceutical analysis and bioanalytics. So far, he has published 88 peer-reviewed research articles, 27 review articles, six books and more than 95 articles in ‚on-the-bench‘ journals. With www.chemnixblog.de, www.analyticsplus.org and others he actively operates educational online platforms.